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GARP Monoclonal Antibody (YGIC86), eFluor™ 450, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£111.00 - £288.00

Specifications

Antigen GARP
Clone YGIC86
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15301840
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Affymetrix eBioscience
48-9891-82
100 μg
£288.00
100µg
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Estimated Shipment: 22-05-2024
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15391830
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Affymetrix eBioscience
48-9891-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The YGIC86 monoclonal antibody reacts with mouse Glycoprotein A Repetitions Predomit (GARP, also known as Lrrc32 or Garpin). GARP is an approximately 80 kDa glycoprotein that is expressed on the cell surface. Using northern blot, RT-PCR or microarray analyses, the expression of GARP has been reported in placenta, lung, kidney, heart, ovary, liver, skeletal muscle, and pancreas. Protein expression has been observed on megakaryocytes, platelets and activated regulatory T (Treg) cells. The expression of GARP on Treg cells has been reported to be necessary for the suppressive function of Treg cells, possibly related to its role as a cell surface receptor for LAP/TGF beta. When looking for expression of GARP on platelets, it is recommended to use the Foxp3 Staining Buffer Set (cat. 00-5523) to fix the platelets before staining with this YGIC86 monoclonal antibody. Fixation/permeabilization is not necessary when staining Treg cells. YGIC86 does not cross-react to rat GARP. Applications Reported: This YGIC86 antibody has been reported for use in flow cytometric analysis. Applications Tested: This YGIC86 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

GARP Monoclonal antibody specifically detects GARP in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

GARP
0.2 mg/mL
Monoclonal
Liquid
RUO
434215
Primary
4° C, store in dark, DO NOT FREEZE!
YGIC86
Flow Cytometry
eFluor 450
Rat
Mouse
IgG2a κ
Affinity chromatography
Antibody
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