GARP Rat anti-Human, PerCP-eFluor 710, Clone: G14D9, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9882-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15509466

Quantity Price
1 £ 87.96 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Quantity 25 Tests
Applications Flow Cytometry
Antigen GARP
Clone G14D9
Gene Alias LRRC32, Garpin
Isotype IgG2a
Concentration 5μL (0.125μg)/test
Format Conjugated
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The G14D9 monoclonal antibody reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin). GARP is an approximately 80kDa glycoprotein that is expressed on the cell surface. Using northern blot, RT-PCR or microarray analyses, the expression of GARP has been reported in placenta, lung, kidney, heart, ovary, liver, skeletal muscle, and pancreas. Protein expression has been observed on megakaryocytes, platelets and activated regulatory T (Treg) cells. The expression of GARP on the surface of activated Treg cells has been reported to be necessary for their suppressive function, possibly related to its role as a cell surface receptor for LAP/TGF beta.