GARP Rat anti-Human, PE-Cy7, Clone: G14D9, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9882-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15548686

Quantity Price
1 £ 84.99 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Gene Alias LRRC32, Garpin
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Antigen GARP
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated
Isotype IgG2a
Regulatory Status RUO
Concentration 5μL (1.0μg)/test
Primary or Secondary Primary
Species Reactivity Human
Conjugate PE-Cy7
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal
Clone G14D9
Host Species Rat

The G14D9 monoclonal antibody reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin). GARP is an approximately 80kDa glycoprotein that is expressed on the cell surface. Using northern blot, RT-PCR or microarray analyses, the expression of GARP has been reported in placenta, lung, kidney, heart, ovary, liver, skeletal muscle, and pancreas. Protein expression has been observed on megakaryocytes, platelets and activated regulatory T (Treg) cells. The expression of GARP on the surface of activated Treg cells has been reported to be necessary for their suppressive function, possibly related to its role as a cell surface receptor for LAP/TGF beta.