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GANT 58, Tocris Bioscience™

GLI1 antagonist; inhibits Hedgehog (Hh) signaling

Brand:  Tocris (Bio-Techne) 388910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13463764

  • £151.80 / 10mg


Estimated Shipment
03-09-2018
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Description

Description

GLI antagonist that inhibits GLI1-induced transcription (IC50 = 5μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo.
Specifications

Chemical Identifiers

64048-12-0
392.48
2,3,4,5-Tetra(4-pyridyl)thiophene
C24H16N4S
USWLOKMMUTWFMD-UHFFFAOYSA-N
253078

Specifications

GANT 58
64048-12-0
C24H16N4S
USWLOKMMUTWFMD-UHFFFAOYSA-N
4-(2,4,5-tripyridin-4-ylthiophen-3-yl)pyridine
253078
10mg
>99%
2,3,4,5-Tetra(4-pyridyl)thiophene
C1=CN=CC=C1C2=C(SC(=C2C3=CC=NC=C3)C4=CC=NC=C4)C5=CC=NC=C5
392.48
392.48
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