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Galectin 3, clone: eBioM3/38 (M3/38), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5301-85

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15207417

  • £163.75 / 500µg


Estimated Shipment
30-07-2018
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Description

Description

Description: The eBioM3/38 antibody reacts with mouse Galectin-3 (Mac-2). Galectins are a family of animal lectins which appear to exhibit a variety of biological functions. Galectin 3 (aka LGALS3, galactose-specific soluble lectin 3, Mac-2, L-29) is one of the more extensively studied members of this family and is a 30kDa beta-galactoside-binding protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homo-oligomerized. Galectin 3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.This monoclonal antibody eBioM3/38 crossreacts to human Galectin-3 (LGALS3).Applications Reported: This eBioM3/38 (M3/38) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), immunohistology staining of frozen tissue sections, immunohistology staining of paraffin embedded tissue sections, and ELISA.Applications Tested: This eBioM3/38 (M3/38) antibody has been tested by flow cytometric analysis of mouse PECs (thioglycollated elicied peritioneal cells). This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Galectin-3
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P17931, P16110
BP (IgE Binding Protein), Mac-2, CBP-30, L-29
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
ELISAþFlow CytometryþImmunohistochemistryþImmunohistochemistry (Frozen)þImmunoprecipitationþWestern Blot
eBioM3/38 (M3/38)
Unconjugated
LGALS3
Purified
LGALS3
IgG2a, kappa
500μg
Store at 2-8°C.
Primary
3958
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