G-CSF Monoclonal Antibody (9B4CSF), eFluor™ 660, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Product Code	Brand	Quantity
15550037	Affymetrix eBioscience 50-7353-82	100 μg
15540037	Affymetrix eBioscience 50-7353-80	25 μg

Description

Description: This 9B4CSF monoclonal antibody reacts with mouse G-CSF (Granulocyte Colony-Stimulating Factor), a growth factor that stimulates the proliferation, differentiation, and mobilization of hematopoetic stem cells. It is expressed by monocytes, macrophages, and bone marrow stromal cells, and can also be induced in fibroblasts by IL-17A. Unlike GM-CSF and IL-3, which can stimulate cells of multiple lineages, G-CSF activity is limited to neutrophilic granulocytes. G-CSF is essential to the maintece of neutrophil counts during homeostasis, and low basal levels of the protein are detectable in the serum of healthy individuals. Circulating levels become elevated rapidly upon infection, as G-CSF is also important for the activation and mobilization of mature neutrophils during the innate immune response. G-CSF therapy is commonly used to treat neutropenia following bone marrow transplant or chemotherapy. This 9B4CSF antibody has been demonstrated to cross-react with human G-CSF. Applications Reported: This 9B4CSF antibody has been reported for use in flow cytometric analysis, and intracellular staining followed by flow cytometric analysis. Applications Tested: This 9B2-8°CSF antibody has been tested by intracellular staining followed by flow cytometric analysis of in vitro-cultured and stimulated mouse monocytes/macrophages. This can be used at less than or equal to 0.06 μg per test.

G-CSF Monoclonal antibody specifically detects G-CSF in Mouse samples. It is validated for Flow Cytometry.

Specifications

• Antigen: G-CSF
• Concentration: 0.2 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Gene Accession No.: P09920
• Gene Symbols: Csf3
• Primary or Secondary: Primary
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Gene: Csf3

• Clone: 9B4CSF
• Applications: Flow Cytometry
• Conjugate: eFluor 660
• Host Species: Rat
• Target Species: Mouse
• Gene ID (Entrez): 12985
• Isotype: IgG2a κ
• Purification Method: Affinity chromatography
• Product Type: Antibody

For Research Use Only.