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FZD8 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA560901
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: GSLYSDVSTG LTWRSGTASS VSYPKQMPLS QV Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.Specifications
FZD8 | |
Polyclonal | |
Unconjugated | |
Fzd8 | |
frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8325 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry, Western Blot | |
0.4 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9H461 | |
Fzd8 | |
Recombinant protein corresponding to Human FZD8 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only