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Tocris Bioscience™ FR 180204

Selective ERK inhibitor

Brand:  Tocris Bioscience™ 370610

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13453454

  • £233.73 / 10mg

Estimated Shipment date
from Supplier 27-03-2020

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Description

Description

Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM).
Specifications

Specifications

FR 180204
>98
10mg
FR 180204
327.34
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