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FOXP3 Monoclonal Antibody (FJK-16s), eFluor™ 506, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£292.00
Specifications
Clone | FJK-16s |
---|---|
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | eFluor 506 |
Description
Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA). KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM). Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells. This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells. MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling. Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct. Applications Reported: This 2F1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2F1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.
FOXP3 Monoclonal antibody specifically detects FOXP3 in Bovine, Canine, Feline, Mouse, Porcine, Rat samples. It is validated for Flow Cytometry.Specifications
FJK-16s | |
Flow Cytometry | |
eFluor 506 | |
Rat | |
Bovine, Canine, Feline, Mouse, Porcine, Rat | |
100037405, 20371, 317382, 444998, 491876, 506053 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Foxp3 |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
Q99JB6 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.