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FOXP3 Monoclonal Antibody (FJK-16s), eFluor™ 506, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£292.00

Specifications

Clone FJK-16s
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
Conjugate eFluor 506
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15500697
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Affymetrix eBioscience
69-5773-82
100 μg
£292.00
100µg
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Description

Description

Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA). KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM). Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells. This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells. MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling. Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct. Applications Reported: This 2F1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2F1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

FOXP3 Monoclonal antibody specifically detects FOXP3 in Bovine, Canine, Feline, Mouse, Porcine, Rat samples. It is validated for Flow Cytometry.
Specifications

Specifications

FJK-16s
Flow Cytometry
eFluor 506
Rat
Bovine, Canine, Feline, Mouse, Porcine, Rat
100037405, 20371, 317382, 444998, 491876, 506053
Primary
4° C, store in dark, DO NOT FREEZE!
Foxp3
0.2 mg/mL
Monoclonal
Liquid
RUO
Q99JB6
IgG2a κ
Affinity chromatography
Antibody
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