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FOXJ1 Mouse anti-Human, Mouse, Clone: 2A5, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9965-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15248287

  • £140.02 / 100µg


EU Stock 8
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Disclaimers:

For Research Use Only.


Description

Description

This 2A5 monoclonal antibody reacts with Foxj1, a 50kDa member of the Forkhead-box (FOX) family of winged-helix transcription factors. Expression of Foxj1 is high in ciliated epithelial cells and low in naïve T and B cells, where cellular activation results in downregulation of the factor. Foxj1 modulates germinal center formation and Th1 activation by repressing NFκB through IκBβ induction. As such, this transcription factor has been suggested to antagonize autoimmune reactions such as systemic lupus erythematosus and rheumatoid arthritis. In addition, Foxj1 has been linked to the formation of motile cilia in epithelial cells.
Specifications

Specifications

FOXJ1
2A5
Unlabeled
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
HFH-4, HFH4, Fox J1
IgG1
RUO
Primary
Murine
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