FOXJ1 Mouse anti-Human, Mouse, Clone: 2A5, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9965-82

Product Code. 15248287

Disclaimers:

For Research Use Only.

Description

This 2A5 monoclonal antibody reacts with Foxj1, a 50kDa member of the Forkhead-box (FOX) family of winged-helix transcription factors. Expression of Foxj1 is high in ciliated epithelial cells and low in naïve T and B cells, where cellular activation results in downregulation of the factor. Foxj1 modulates germinal center formation and Th1 activation by repressing NFκB through IκBβ induction. As such, this transcription factor has been suggested to antagonize autoimmune reactions such as systemic lupus erythematosus and rheumatoid arthritis. In addition, Foxj1 has been linked to the formation of motile cilia in epithelial cells.

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Specifications

• Antigen: FOXJ1
• Clone: 2A5
• Conjugate: Unlabeled
• Format: Purified
• Host Species: Murine
• Quantity: 100μg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Western Blot
• Concentration: 0.5mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Gene Alias: HFH-4, HFH4, Fox J1
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine