FOXJ1 Mouse anti-Human, Mouse, Clone: 2A5, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9965-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15238287

Quantity Price
1 £ 60.53 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification


Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blot
Host Species Murine
Clone 2A5
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Isotype IgG1
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Gene Alias HFH-4, HFH4, Fox J1
Monoclonal or Polyclonal Monoclonal
Format Purified
Species Reactivity Human, Mouse
Regulatory Status RUO
Quantity 25μg
Antigen FOXJ1

This 2A5 monoclonal antibody reacts with Foxj1, a 50kDa member of the Forkhead-box (FOX) family of winged-helix transcription factors. Expression of Foxj1 is high in ciliated epithelial cells and low in naïve T and B cells, where cellular activation results in downregulation of the factor. Foxj1 modulates germinal center formation and Th1 activation by repressing NFκB through IκBβ induction. As such, this transcription factor has been suggested to antagonize autoimmune reactions such as systemic lupus erythematosus and rheumatoid arthritis. In addition, Foxj1 has been linked to the formation of motile cilia in epithelial cells.