Fluorescein-ERM (LRRKtide)

Fluorescein-ERM (LRRKtide)

Brand:  Invitrogen PV4901

Product Code. 10258044

Description

A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.

For use in combination with the LanthaScreen™ Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.

Specifications

• Amino Acid Sequence: Fluorescein-GAGRLGRDKYKTLRQIRQ
• Content And Storage: 400 μM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light.
• Quantity: 1 mg
• Substrate Properties: Peptide-Based Substrate
• Target Enzyme: Serine/Threonine Kinases
• Label or Dye: FITC (Fluorescein)
• Shipping Condition: Dry Ice
• Validated Kinases: LRRK2

• Assay Entry: Biochemical terbium phospho-specific activity
• Detection Method: Fluorescent
• Substrate: ERM (LRRKtide)
• Substrate Type: Kinase Substrate
• Gene ID (Entrez): 120892
• Molecular Weight (g/mol): 2475.8 Da
• Target Entry: LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2

For Research Use Only. Not for use in diagnostic procedures.