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Fludarabine, Tocris Bioscience™

Purine analog; inhibits DNA synthesis

Brand:  Tocris (Bio-Techne) 349550

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13463074

  • £427.72 / 50mg


Estimated Shipment
29-11-2018
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Description

Description

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo.
Specifications

Chemical Identifiers

21679-14-1
285.235
fludarabine, f-ara-a, 2-fluoro ara-a, 9-beta-d-arabinofuranosyl-2-fluoroadenine, fludarabine inn, fludarabinum latin, fludarabina spanish, fludarabina, fludarabinum, 2r,3s,4s,5r-2-6-amino-2-fluoro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol
(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
C10H12FN5O4
HBUBKKRHXORPQB-FJFJXFQQSA-N
657237
C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)F

Specifications

Fludarabine
21679-14-1
fludarabine, f-ara-a, 2-fluoro ara-a, 9-beta-d-arabinofuranosyl-2-fluoroadenine, fludarabine inn, fludarabinum latin, fludarabina spanish, fludarabina, fludarabinum, 2r,3s,4s,5r-2-6-amino-2-fluoro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol
C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)F
285.235
285.23
50mg
C10H12FN5O4
HBUBKKRHXORPQB-FJFJXFQQSA-N
(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
657237
>99%
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