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Thermo Scientific Chemicals Fluconazole, 98%

Catalog Number p-7077555
52.65 GBP valid until 2024-12-31
Use promo code "22914" to get your promotional price.


47.00 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.


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Quantity:
1 g
5 g
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
86386-73-4
C13H12F2N6O
306.27
RFHAOTPXVQNOHP-UHFFFAOYSA-N
fluconazole, diflucan, triflucan, elazor, biozolene, biocanol, fungata, fluconazol, fluconazolum, flucazol
3365
CHEBI:46081
2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
86386-73-4
C13H12F2N6O
306.27
RFHAOTPXVQNOHP-UHFFFAOYSA-N
fluconazole, diflucan, triflucan, elazor, biozolene, biocanol, fungata, fluconazol, fluconazolum, flucazol
3365
CHEBI:46081
2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O

Fluconazole, 98%, CAS # 86386-73-4, is a synthetic triazole with antifungal activity against some species of Candida. It also shows inhibitory activity against cytochrome P-450 enzymes and it is a demethylase.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Fluconazole, 98% is a triazole compound showing antifungal activity mainly against Candida, Coccidioides, and Cryptococcus species

• It has been shown to inhibit fungal cytochrome P-450 sterol C-14 α-demethylation, resulting in the accumulation of fungal 14 α-methyl sterols, the loss of normal fungal sterols, and associated fungistatic activity

• It also inhibits cytochrome P450 family 2 subfamily c member 9 (CYP2C9)

• Mammalian cell demethylation is much less susceptible to fluconazole inhibition

Applications

• Fluconazole has fungistatic activity against many fungal strains including Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis, and Cryptococcus neoformans.

• Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene

• In biological experiments, this compound has been used to assess minimum inhibitory concentration in (MIC)-fungal assays

• It has also been used as a positive control in antifungal assay of plants

TRUSTED_SUSTAINABILITY
Melting Point 137.0°C to 141.0°C
Loss on Drying 1% max. (105°C, 3 h)
Infrared Spectrum Authentic
Assay Percent Range 97.5% min. (HPLC)
Packaging Glass Bottle
Quantity 1 g
Solubility Information Solubility in water: <1mg/mL at 25 deg c. Other solubilities: solubility in ethanol: 61mg/mL at 25 deg c, solubility in dmso: 61mg/mL at 25 deg c
Formula Weight 306.27
Percent Purity 98%
Chemical Name or Material Fluconazole
compliance-icons compliance-icons
Product Identifier
  • Fluconazole
Signal Word
  • Danger
Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Reproductive toxicity Category 1B
  • Skin corrosion/irritation Category 2
Hazard Statement
  • H360D-May damage the unborn child.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H302-Harmful if swallowed.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P362-Take off contaminated clothing.

RUO – Research Use Only

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