Fibronectin Mouse anti-Human, Clone: FN-3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9869-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238197

Quantity Price
1 £ 121.67 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL
Antigen Fibronectin
Species Reactivity Human
Regulatory Status RUO
Clone FN-3
Conjugate Unlabeled
Format Purified
Primary or Secondary Primary
Host Species Mouse
Quantity 100μg
Isotype IgG1

The FN-3 monoclonal antibody recognizes human fibronectin, a component of the extracellular matrix. This high molecular weight protein (almost 400 kDa) exists as an extracellular and a soluble plasma form. Fibronectin functions in cell adhesion and migration via integrins present on the interacting cell. Fibronectin also associates with collagen, actin and fibrins. In malignancies, fibronectin protein levels can be altered. In lung carninomas, expression is decreased. The FN-3 antibody recognizes a determinant on human cellular but not plasma fibronectin; this recognition is not lost upon trypsin treatment. Furthermore, FN-3 antibody has been shown to crossreact to bovine fibronectin.