Fibronectin Mouse anti-Human, Clone: FN-3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9869-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15228197

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 02-05-2017
Add to basket


Description and Specification

Specification

Host Species Mouse
Concentration 0.5mg/mL
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Format Purified
Primary or Secondary Primary
Clone FN-3
Isotype IgG1
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.
Quantity 25μg
Antigen Fibronectin
Conjugate Unlabeled

The FN-3 monoclonal antibody recognizes human fibronectin, a component of the extracellular matrix. This high molecular weight protein (almost 400 kDa) exists as an extracellular and a soluble plasma form. Fibronectin functions in cell adhesion and migration via integrins present on the interacting cell. Fibronectin also associates with collagen, actin and fibrins. In malignancies, fibronectin protein levels can be altered. In lung carninomas, expression is decreased. The FN-3 antibody recognizes a determinant on human cellular but not plasma fibronectin; this recognition is not lost upon trypsin treatment. Furthermore, FN-3 antibody has been shown to crossreact to bovine fibronectin.