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Fibronectin Mouse anti-Human, Alexa Fluor 488, Clone: FN-3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9869-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15332090

  • £186.31 / 25µg


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

The FN-3 monoclonal antibody recognizes human fibronectin, a component of the extracellular matrix. This high molecular weight protein (almost 400 kDa) exists as an extracellular and a soluble plasma form. Fibronectin functions in cell adhesion and migration via integrins present on the interacting cell. Fibronectin also associates with collagen, actin and fibrins. In malignancies, fibronectin protein levels can be altered. In lung carninomas, expression is decreased. The FN-3 antibody recognizes a determinant on human cellular but not plasma fibronectin; this recognition is not lost upon trypsin treatment. Furthermore, FN-3 antibody has been shown to crossreact to bovine fibronectin.
Specifications

Specifications

Fibronectin
FN-3
Alexa Fluor 488
Conjugated
IgG1
RUO
Primary
Human
Immunohistochemistry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal