Fibronectin Mouse anti-Human, Alexa Fluor 488, Clone: FN-3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9869-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15332090

Quantity Price
1 £ 186.31 / 25µg
EU Stock 21
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Description and Specification

Specification

Host Species Murine
Conjugate Alexa Fluor 488
Format Conjugated
Concentration 0.5mg/mL
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Clone FN-3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG1
Applications Immunocytochemistry
Applications Immunohistochemistry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen Fibronectin
Quantity 100μg
Species Reactivity Human

The FN-3 monoclonal antibody recognizes human fibronectin, a component of the extracellular matrix. This high molecular weight protein (almost 400 kDa) exists as an extracellular and a soluble plasma form. Fibronectin functions in cell adhesion and migration via integrins present on the interacting cell. Fibronectin also associates with collagen, actin and fibrins. In malignancies, fibronectin protein levels can be altered. In lung carninomas, expression is decreased. The FN-3 antibody recognizes a determinant on human cellular but not plasma fibronectin; this recognition is not lost upon trypsin treatment. Furthermore, FN-3 antibody has been shown to crossreact to bovine fibronectin.