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Thermo Scientific™ 5-Fluoroorotic Acid

Detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase with Thermo Scientific™ 5-Fluoroorotic Acid, used in yeast molecular genetics.

£88.75 - £368.00

Specifications

Chemical Name or Material 5-Fluoroorotic Acid
Product Type 5-Fluoroorotic Acid
Form Powder
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
10609920
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Thermo Scientific™
R0811
1 g
£88.75
1g
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Estimated Shipment: 15-04-2024
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10619920
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Thermo Scientific™
R0812
5 g
£368.00
5g
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Description

Description

5-Fluoroorotic Acid is a yeast with an active URA3 gene (Ura+) converts 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3), and E. coli (pyrF).

Convertion of 5-FOA to fluorodeoxyuridine

Convertion of 5-FOA to fluorodeoxyuridine

Specifications

Specifications

5-Fluoroorotic Acid
5-Fluoroorotic Acid
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Product Certifications

For Research Use Only. Not for use in diagnostic procedures.