missing translation for 'onlineSavingsMsg'
Learn More

FDC, Biotin, clone: CNA.42, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-9968-80

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15547396

  • £61.31 / 25µg


Estimated Shipment date
from Supplier 26-06-2018
Add to basket

Description

Description

Description: The monoclonal antibody CNA.42 recognizes a unique carbohydrate epitope found on follicular dendritic cells (FDCs) from a variety of species. FDCs are large cells in germinal centers (GCs) of primary and lymphoid tissues. They present non-processed antigen and switch off apoptosis of B cells through a selection process resulting in selection of memory B cells. FDCs express many B cell markers such as CD21 (long isoform), CD23 and CD35. A role for FDCs as been shown in various infectious diseases such as AIDS and transmissible spongiform encephalitis. Staining with this CNA.42 monoclonal antibody is mainly restricted to the plasma membrane but in limited cases may also be cytoplasmic (as seen in mast cells).This monoclonal has been shown to be a useful reagent for both flow cytometry and IHC analysis.Applications Reported: This CNA.42 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining of frozen and formalin-fixed paraffin embedded tissue sections.Applications Tested: This CAN.42 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tonsil tissue using high pH antigen retrieval. This antibody can be used at less than or equal to 30 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

FDC
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
FDC, Follicular Dendritic Cells
IgM
25μg
Store at 2-8°C. Do not freeze.
Primary
Human
Western Blot
CNA.42
Biotin
Conjugated
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Videos

For Research Use Only.