FDC Mouse anti-Human, Biotin, Clone: CNA.42, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-9968-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15547396

Quantity Price
1 £ 59.25 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Quantity 25μg
Primary or Secondary Primary
Gene Alias Follicular dendritic cell
Host Species Mouse
Applications Flow Cytometry
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Format Conjugated
Conjugate Biotin
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human
Isotype IgM
Storage Requirements Store at 2-8°C. Do not freeze.
Clone CNA.42
Antigen FDC
Regulatory Status RUO

The monoclonal antibody CNA.42 recognizes a unique carbohydrate epitope found on follicular dendritic cells (FDCs) from a variety of species. FDCs are large cells in germinal centers (GCs) of primary and lymphoid tissues. They present non-processed antigen and switch off apoptosis of B cells through a selection process resulting in selection of memory B cells. FDCs express many B cell markers such as CD21 (long isoform), CD23 and CD35. A role for FDCs as been shown in various infectious diseases such as AIDS and transmissible spongiform encephalitis. Staining with this CNA.42 monoclonal antibody is mainly restricted to the plasma membrane but in limited cases may also be cytoplasmic (as seen in mast cells).

This monoclonal has been shown to be a useful reagent for both flow cytometry and IHC analysis.