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FceR1 alpha Mouse anti-Human, PerCP-eFluor™ 710, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-5899-41

Code : NEW

Additional Details : Weight : 0.23750kg

Product Code. 15589306

  • £97.50 / 25 tests

Estimated Shipment date
from Supplier 23-03-2020

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Description

Description

00-8222) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.
Specifications

Specifications

FceR1 alpha
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P12319
RP11-550P17.3, FCE1A, FcERI
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
AER-37 (CRA1)
PerCP-eFluor™ 710
FCER1A
Liquid
FCER1A
IgG2b, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
2205
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