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FceR1 alpha Monoclonal Antibody (AER-37 (CRA1)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 46-5899-42
200.01 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.
Code : NEW
Additional Details : Weight : 0.23750kg
Description
The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta ., and gamma .; only the alpha subunit is glycosylated.
FceR1 alpha Monoclonal antibody specifically detects FceR1 alpha in Human samples. It is validated for Flow Cytometry.Specifications
FceR1 alpha | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
P12319 | |
FCER1A | |
Affinity chromatography | |
RUO | |
2205 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
AER-37 (CRA1) | |
PerCP-eFluor 710 | |
FCER1A | |
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3 | |
Mouse | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG2b κ |
For Research Use Only.