Fc epsilon Receptor 1 alpha (FceRI) Mouse anti-Human, PE-eFluor 610, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 61-5899-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15540537

Quantity Price
1 £ 167.38 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Format Conjugated
Isotype IgG2b
Quantity 100 tests
Gene Alias FceRI alpha, high affinity IgE receptor
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Regulatory Status RUO
Conjugate PE-eFluor 610
Monoclonal or Polyclonal Monoclonal
Clone AER-37 (CRA1)
Concentration 5μL (0.25μg)/test
Species Reactivity Human
Host Species Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Primary or Secondary Primary
Antigen Fc epsilon Receptor 1 alpha (FceRI)

The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI apha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.