Fc epsilon Receptor 1 alpha (FceRI) Mouse anti-Human, PE-Cy7, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-5899-42

100TEST Anti-Human Fc epsilon Receptor I alpha (FceR1) PE-Cyanine7

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15538596

Quantity Price
1 £ 217.47 / 100 tests
Estimated Shipment date
from Supplier 31-03-2017
Add to basket


Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Antigen Fc epsilon Receptor 1 alpha (FceRI)
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias FceRI alpha, high affinity IgE receptor
Host Species Mouse
Applications Flow Cytometry
Isotype IgG2b
Quantity 100 tests
Regulatory Status RUO
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Clone AER-37 (CRA1)
Concentration 5μL (0.25μg)/test
Conjugate PE-Cy7

The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI apha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.