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FceR1 alpha, eFluor 450, clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-5899-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15519786

  • £189.69 / 100 tests


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

Description: The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI apha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.Applications Reported: This AER-37 (CRA1) antibody has been reported for use in flow cytometric analysis.Applications Tested: This AER-37 (CRA1) antibody has been pre-titrated and tested by flow cytometric analysis or normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Fc epsilon Receptor 1 alpha (FceRI)
AER-37 (CRA1)
eFluor 450
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
FceRI alpha, high affinity IgE receptor
IgG2b
RUO
Primary
Human
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