Fc epsilon Receptor 1 alpha (FceRI) Mouse anti-Human, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-5899-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15267587

Quantity Price
1 £ 152.25 / 100µg
EU Stock 1
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Description and Specification

Specification

Antigen Fc epsilon Receptor 1 alpha (FceRI)
Applications Flow Cytometry
Regulatory Status RUO
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human
Primary or Secondary Primary
Storage Requirements Store at 2-8°C.
Clone AER-37 (CRA1)
Monoclonal or Polyclonal Monoclonal
Gene Alias FceRI-a, FceRI-alpha, FceRI alpha, high affinity IgE receptor
Quantity 100μg
Isotype IgG2b
Concentration 0.5mg/mL
Host Species Mouse
Conjugate Unlabeled

The AER-37 monoclonal antibody reacts with the FcεRIα subunit, an IgE-binding subunit lacking signal-transducing ability. FcεRIα is expressed on mast and basophil cells and is upregulated by the presence of IgE. FcεRIα forms a tetrameric complex with one β and two γ subunits. The β and γ subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.