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FceR1 alpha, clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5899-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15267587

  • £156.85 / 100µg


EU Stock 5
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Description

Description

Description: The AER-37 monoclonal antibody reacts with the FcεRIalpha subunit, an IgE-binding subunit lacking signal-transducing ability. FcεRIalpha is expressed on mast and basophil cells and is upregulated by the presence of IgE. FcεRIalpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.Applications Reported: The AER-37 (CRA1) antibody has been reported for use in flow cytometric analysis. It has been reported to not block IgE binding.Applications Tested: The AER-37 (CRA1) antibody has been tested by flow cytometric analysis of peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Fc epsilon Receptor 1 alpha (FceRI)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P12319
RP11-550P17.3, FCE1A, FcERI
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
AER-37 (CRA1)
Unconjugated
FCER1A
Purified
FCER1A
IgG2b, kappa
100μg
Store at 2-8°C.
Primary
2205
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