Fc epsilon Receptor 1 alpha (FceRI) Mouse anti-Human, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-5899-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15257587

Quantity Price
1 £ 66.65 / 25µg
Estimated Shipment date
from Supplier 07-06-2017
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Description and Specification

Specification

Antigen Fc epsilon Receptor 1 alpha (FceRI)
Applications Flow Cytometry
Clone AER-37 (CRA1)
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias FceRI-a, FceRI-alpha, FceRI alpha, high affinity IgE receptor
Host Species Murine
Isotype IgG2b
Quantity 25μg
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

The AER-37 monoclonal antibody reacts with the FcεRIα subunit, an IgE-binding subunit lacking signal-transducing ability. FcεRIα is expressed on mast and basophil cells and is upregulated by the presence of IgE. FcεRIα forms a tetrameric complex with one β and two γ subunits. The β and γ subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.