Fc epsilon Receptor 1 alpha (FceRI) Mouse anti-Human, Biotin, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-5899-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15259919

Quantity Price
1 £ 86.73 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Host Species Mouse
Gene Alias FceRI alpha, high affinity IgE receptor
Regulatory Status RUO
Concentration 0.5mg/mL
Applications Flow Cytometry
Species Reactivity Human
Format Conjugated
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Isotype IgG2b
Clone AER-37 (CRA1)
Conjugate Biotin
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Antigen Fc epsilon Receptor 1 alpha (FceRI)
Storage Requirements Store at 2-8°C. Do not freeze.

The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI apha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.