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FceR1 alpha, Functional Grade, clone: MAR-1, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5898-85

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15258687

  • £244.23 / 500Āµg


Estimated Shipment
31-07-2018
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Description

Description

Description: The MAR-1 monoclonal antibody reacts with the Fc epsilon Receptor I alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI alpha; is expressed on mast and basophil cells and is up-regulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.Applications Reported: The MAR-1 antibody has been reported for use in flow cytometric analysis. It has also been reported in blocking of IgE to Fc epsilon Receptor and degranulation of mast cells.Applications Tested: The MAR-1 antibody has been tested by flow cytometric analysis of the MC/9 cell line (a mouse mast cell line). This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

Fc epsilon Receptor 1 alpha (FceRI)
Monoclonal
1mg/mL
PBS with no preservative; pH 7.2
P20489
RP11-550P17.3, FCE1A, FcERI
Armenian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow CytometryĆ¾Functional Assay
MAR-1
Functional Grade
Fcer1a
Purified
Fcer1a
IgG
500μg
Store at 2-8°C.
Primary
14125
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