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F4/80 Antigen Rat anti-Mouse, Clone: BM8, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-4801-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15268627

  • £182.82 / 500µg


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For Research Use Only.


Specifications

Description

The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 125kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo.
Description & Specifications

Specifications

F4/80 Antigen
BM8
Unlabeled
aqueous buffer, no sodium azide
Rat
500μg
Store at 2-8°C.
Monoclonal
Flow Cytometry
1mg/mL
Purified
Pan Macrophage Marker
IgG2a
RUO
Primary
Murine