Thermo Scientific™ EZ-Link™ Sulfo-NHS-SS-Biotin and Labeling Kits

Biotinylate protein amines with this cleavable, mid-length (24.3A), water-soluble, NHS-ester biotinylation reagent containing a cleavable disulfide bond in the spacer arm.

Brand: Thermo Scientific™

Manufacturer Part Number: 21331

UNSPSC: 41115824

Code: PN

Additional Details:
Additional Details: Weight: 1.00000kg

Product Code. 11811205

Quantity Price
1 £ 338.0 / 100mg
EU Stock 57
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Description and Specification


Storage Requirements -20°C protected from moisture
Formulation Sulfo-NHS ester of biotin with an ethyl-1,3-dithioproprionate spacer
Cleavable Yes
Sufficient For Approx. 50 uses to label a total of 1099mg of IgG using typical conditions
Molecular Weight 606.69
Spacer Arm Length 24.3
Membrane Permeable No
Description EZ-Link Sulfo-NHS-SS-Biotin
PEGylated No
Chemical Reactivity Amine
Quantity 100mg
Water Soluble Yes


  • Cleavable analog of Sulfo-NHS-LC-Biotin
  • Can remove biotin label by cleaving spacer disulfide bond with reducing agents, such as DTT
  • Ideal for affinity purification experiments that require efficient elution from immobilized avidin supports (cleaving disulfide bond releases proteins)
  • Long spacer arm reduces steric hindrance for binding interactions


Technical documents