Estrogen Receptor beta Mouse anti-Human, Clone: MC10, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9336-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15517596

Quantity Price
1 £ 55.59 / 25µg
EU Stock 1
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Description and Specification

Specification

Antigen Estrogen Receptor beta
Applications ELISA
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunoprecipitation
Applications Microscopy
Applications Western Blot
Clone MC10
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Murine
Isotype IgG2a
Quantity 25μg
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

The MC10 monoclonal antibody recognizes all forms of human estrogen receptor (ER) beta. ER beta is a member of a superfamily of nuclear receptors, which are ligand-dependent transcription factors. ER beta like ER alpha, becomes activated by binding the hormone estrogen, causing a dissociation from chaperone proteins and subsequent dimerization with either ER beta or ER alpha. Unlike ER alpha, the result of ER beta signaling is thought to be anti-proliferative and proapoptotic. The MC10 clone recognizes full length ER beta as well as each of its splice variants.