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EphB1 (ephrin B1) Rat anti-Mouse, Clone: 25H11, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5300-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15277407

  • £136.24 / 100µg


Estimated Shipment
07-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 25H11 recognizes mouse Ephrin B1, a 47kDa membrane protein. Ephrin B1 belongs to a family of ephrins composed of type A (linked to the cell membrane through a glycosylphosphatidyl inositol group) or type B (transmembrane) proteins. The type B ephrins consist of 3 members (B1, B2, and B3) each of which contains a cytoplasmic domain containing tyrosine residues that can be phosphorylated. Ephrin B and ephrin B receptors (Eph B) can interact to potentiate bidirectional downstream signaling between cells expressing either or both the ligand and receptor. Ephrins have been shown to play a role in neural crest cell development through both neurogenesis and neural migration, as well as development of kidney and heart cyto-architecture. Overexpression of type B ephrins in cancer cells is associated with increased vascularity and highly invasive tumors.
Description & Specifications

Specifications

EphB1 (ephrin B1)
25H11
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
100μg
Store at 2-8°C.
Monoclonal
Immunoprecipitation
0.5mg/mL
Purified
EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2, LERK 2
IgG2a
RUO
Primary
Murine