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EO 1428, Tocris Bioscience™

Selective inhibitor of p38α and p38β2

Brand:  Tocris (Bio-Techne) 290810

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13442024

  • £149.85 / 10mg

Estimated Shipment
27-06-2019

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Description

Description

Selective inhibitor of p38α and p38β2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.
Specifications

Chemical Identifiers

321351-00-2
415.715
unii-mv2rhj680o, mv2rhj680o, p38 map kinase inhibitor viii, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone, 2-methylphenyl-4-2-amino-4-bromophenyl amino-2-chlorophenyl methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone, methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl, 4-2-amino-4-bromophenylamino-2-chlorophenyl o-tolyl methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl o-tolyl methanone, 4-2-amino-4-bromo-phenylamino-2-chloro-phenyl-o-tolyl-methanone
[4-(2-amino-4-bromoanilino)-2-chlorophenyl]-(2-methylphenyl)methanone
C20H16BrClN2O
HDCLCHNAEZNGNV-UHFFFAOYSA-N
9801969
CC1=CC=CC=C1C(=O)C2=C(C=C(C=C2)NC3=C(C=C(C=C3)Br)N)Cl

Specifications

EO 1428
321351-00-2
unii-mv2rhj680o, mv2rhj680o, p38 map kinase inhibitor viii, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone, 2-methylphenyl-4-2-amino-4-bromophenyl amino-2-chlorophenyl methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl methanone, methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl 2-methylphenyl, 4-2-amino-4-bromophenylamino-2-chlorophenyl o-tolyl methanone, 4-2-amino-4-bromophenyl amino-2-chlorophenyl o-tolyl methanone, 4-2-amino-4-bromo-phenylamino-2-chloro-phenyl-o-tolyl-methanone
CC1=CC=CC=C1C(=O)C2=C(C=C(C=C2)NC3=C(C=C(C=C3)Br)N)Cl
415.715
415.71
10mg
C20H16BrClN2O
HDCLCHNAEZNGNV-UHFFFAOYSA-N
[4-(2-amino-4-bromoanilino)-2-chlorophenyl]-(2-methylphenyl)methanone
9801969
>98%
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