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EMD 66684, Tocris Bioscience™

Potent, selective non-peptide AT1 antagonist

Brand:  Tocris (Bio-Techne) 184950

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13430124

  • £629.16 / 50mg

Estimated Shipment date
from Supplier 25-03-2020

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Description

Description

Highly potent and very selective non-peptide angiotensin AT1 receptor antagonist (IC50 values are 0.7 and > 10000 nM for AT1 and AT2 receptors respectively). Potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC50 = 0.2 nM) and reduces blood pressure in hypertensive rats.
Specifications

Chemical Identifiers

1216884-39-7
547.06
2-2-butyl-4-oxo-3-2'-2h-tetrazol-5-yl 1,1'-biphenyl-4-yl methyl-3,4-dihydro-5h-imidazo 4,5-c pyridin-5-yl-n,n-dimethylacetamide-hydrogen chloride 1/1, 2-butyl-3,4-dihydro-n,n-dimethyl-4-oxo-3-2'-1h-tetrazol-5-yl 1,1'-biphenyl-4-yl methyl-5h-imidazo 4,5-c pyridine-5-acetamide hydrochloride
2-[2-butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]-N,N-dimethylacetamide;hydrochloride
C28H31ClN8O2
YMFXGXGDHBXTPY-UHFFFAOYSA-N
56972165
CCCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)N(C=C2)CC(=O)N(C)C.Cl

Specifications

50mg
1216884-39-7
2-2-butyl-4-oxo-3-2'-2h-tetrazol-5-yl 1,1'-biphenyl-4-yl methyl-3,4-dihydro-5h-imidazo 4,5-c pyridin-5-yl-n,n-dimethylacetamide-hydrogen chloride 1/1, 2-butyl-3,4-dihydro-n,n-dimethyl-4-oxo-3-2'-1h-tetrazol-5-yl 1,1'-biphenyl-4-yl methyl-5h-imidazo 4,5-c pyridine-5-acetamide hydrochloride
CCCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)N(C=C2)CC(=O)N(C)C.Cl
547.06
547.05
EMD 66684
C28H31ClN8O2
YMFXGXGDHBXTPY-UHFFFAOYSA-N
2-[2-butyl-4-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-c]pyridin-5-yl]-N,N-dimethylacetamide;hydrochloride
56972165
>98%
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