Egr2 Rat anti-Mouse, APC, Clone: erongr2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-6691-80

25UG ANTI-MOUSE EGR2 APC

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15300820

Quantity Price
1 £ 101.0 / 25µg
Estimated Shipment date
from Supplier 21-02-2017
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Description and Specification

Specification

Antigen Egr2
Format Conjugated
Gene Alias KROX20
Host Species Rat
Applications Flow Cytometry (Intracellular Staining)
Isotype IgG2a
Regulatory Status RUO
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Clone erongr2
Conjugate APC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Concentration 0.2mg/mL

This erongr2 monoclonal antibody recognizes mouse early growth response 2 (Egr2, Krox-20). Egr2 is a zinc finger-containing transcription factor that is important for the development of T cells and NKT cells. Egr2 is predominantly expressed in the thymus and nervous system, and it is also upregulated in T cells following TCR-crosslinking. Upregulation in all non-adherent mouse splenocytes has been observed following stimulation with phorbol 12-myristate 13-acetate (PMA) and ionomycin. Egr2 is believed to antagonize T cell activation and has also been reported to promote apoptosis. The erongr2 antibody also appears to modestly stain a subpopulation of T cells and B cells in freshly isolated spleen cells. The erongr2 monoclonal antibody is specific for Egr2 and does not crossreact to Egr3, based on immunoblot analysis.