EGFR (ErbB1) [L861Q] Recombinant Human Protein, Invitrogen™

The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.

Brand:  Invitrogen PR7435A

Product Code. 12654770

Description

The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.

Specifications

• Accession Number: NP_005219.2; L861Q
• Validated Application: Kinase Assay
• Format: Frozen
• Molecular Weight: 90.5kDa
• Storage Requirements: Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Structural Form: Cytoplasmic
• KinaseFamily: EGF Receptor (ErbB) Kinase Family
• Recombinant: Yes

• Expression System: Baculovirus
• For Use With (Application): Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis
• Formulation: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
• Quantity: 100μg
• Regulatory Status: RUO - research use only
• Gene Alias: EGFR (ErbB1) L861Q
• Host Species: Human
• Protein Tag: GST Tag