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EEA1 Mouse anti-Human, Mouse, Rat, Clone: 1G11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9114-80

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15577576

  • £104.00 / 25µg

Estimated Shipment
26-10-2020

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Description

Description

Early endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. Zinc-finger-like domains, reminiscent of those found in nucleic acid binding proteins, are located in the amino and carboxyl-terminal domains of EEA1. The carboxyl-terminal zinc-finger-like-domain is conserved in several other non-nuclear proteins, some of which are also involved in intracellular protein trafficking. In addition, this domain is an authentic zinc-binding domain and is critical to the intracellular localization of EEA1. Membrane association of EEA1 has been shown dependent on phosphatidyl 3-kinase activity, inhibitors of which cause EEA1 to dissociate from early endosomes.
Specifications

Specifications

EEA1
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q15075, Q8BL66
EEA1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse, Rat
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1G11
Unconjugated
EEA1
Liquid
EEA1
IgG1, kappa
25 μg
4° C
Primary
216238, 314764, 8411
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For Research Use Only.