missing translation for 'onlineSavingsMsg'
Learn More

DPO-1, Tocris Bioscience™

Blocker of KV1.5 channel and IKur current

Brand:  Tocris (Bio-Techne) 2533/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13441414

  • £147.15 / 10mg

Estimated Shipment
09-07-2019

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels (IC50 = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IKur over Ito (8-fold), IK1, IKr and IKs (20-fold) in native myocytes and selectivity for rat recombinant KV1.5 over KV3.1 (∽ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.
Specifications

Chemical Identifiers

43077-30-1
340.447
dpo-1, neomenthyldiphenylphosphine oxide, +-neomenthyl diphenylphosphine oxide, 1s,2s,5r-5-methyl-2-1-methylethyl cyclohexyl diphenyl-phosphine oxide, diphenyl phosphine oxide-1, dpo-1, needles nmr, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl diphenyl phosphine oxide, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl phenyl phosphoroso benzene, 1s,2s,5r-5-methyl-2-propan-2-yl cyclohexyl oxo diphenyl-lambda~5~-phosphane, 1s-1?,2?,5?-5-methyl-2-1-methylethyl cyclohexyl diphenylphosphine oxide
[[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene
C22H29OP
BPCNGVCAHAIZEE-COPCDDAFSA-N
21678144
CC1CCC(C(C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C

Specifications

DPO-1
43077-30-1
dpo-1, neomenthyldiphenylphosphine oxide, +-neomenthyl diphenylphosphine oxide, 1s,2s,5r-5-methyl-2-1-methylethyl cyclohexyl diphenyl-phosphine oxide, diphenyl phosphine oxide-1, dpo-1, needles nmr, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl diphenyl phosphine oxide, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl phenyl phosphoroso benzene, 1s,2s,5r-5-methyl-2-propan-2-yl cyclohexyl oxo diphenyl-lambda~5~-phosphane, 1s-1?,2?,5?-5-methyl-2-1-methylethyl cyclohexyl diphenylphosphine oxide
CC1CCC(C(C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C
340.447
340.44
10mg
C22H29OP
BPCNGVCAHAIZEE-COPCDDAFSA-N
[[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene
21678144
>99%
Videos