missing translation for 'onlineSavingsMsg'
Learn More

Thermo Scientific™ Detoxi-Gel™ Endotoxin Removing Gel

Bind and extract endotoxins (lipopolysaccharides or LPS) from antibody or protein samples using bulk resin or columns of immobilized Polymixin B ligand.

Brand:  Thermo Scientific™ 20339

Code : PN

Additional Details : CAS Number : 3943-89-3 Weight : 0.80000kg

 View more versions of this product

Product Code. 11866754

  • £158.67 / 10mL

EU Stock 8
Add to basket



Detoxi-Gel Resin is a beaded agarose support onto which polymixin B has been immobilized. This ligand binds to the lipid A portion of lipopolysaccharides (LPS), which are the dominant form of endotoxins that affect biological samples. Even low levels of endotoxins can be toxic to cells or organisms and must be removed before biological samples can be added to cells for various treatment experiments. Detoxi-Gel Resin provides a quick method for removal of endotoxins from samples. It is available in convenient pre-packed columns and two sizes of slurry for use in small-scale or large-scale processes.


  • Affinity-based – uses immobilized polymixin B to remove endotoxins by binding to their lipid A domains

  • High capacity – 1mL of Detoxi-Gel Resin removes at least 9995 endotoxin units from a 5mL sample containing 10,000 EU of lipopolysaccharide (LPS)

  • Reusable – no loss in binding capacity even after 10 regenerations; requires activation and regeneration with 1% sodium deoxycholate (Part No. 89904)

  • Testing required – protein recovery is dependent upon protein type and concentration; empirical testing is required to validate the method for particular protein samples

  • Versatile – remove endotoxin from protein solutions, cell culture media and pharmacological components


Sodium deoxycholate (Part No. 89904) for resin activation and regeneration.



Detoxi-Gel Endotoxin Removing Gel
Polymixin B on crosslinked 6% beaded agarose slurried in 25% ethyl alcohol
Binding approx. 10,000 endotoxin units of LPS per mL of resin per use

Technical Documents