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Invitrogen™ DCLK1 Recombinant Rabbit Monoclonal Antibody (K01_3L32)

Description
DCLK1 Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Western Blot
DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.
Specifications
Specifications
| Antigen | DCLK1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | K01_3L32 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | DCLK1 |
| Gene Accession No. | O08875, O15075, Q9JLM8 |
| Gene Alias | 1700113D08Rik; 2810480F11Rik; AI836758; Ania4; Calcium/calmodulin-dependent protein kinase type I-like CPG16; CL1; CLICK1; Click-I; CLICK-I beta; Cpg16; Dcamkl1; DCDC3A; Dcl; Dclk; Dclk1; double cortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin like kinase 1; doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; KIAA0369; mKIAA0369; RP11-113P14.1; Serine/threonine-protein kinase DCLK1 |
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