missing translation for 'onlineSavingsMsg'
Learn More

Cytokeratin 19, eFluor 570, clone: BA17, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 41-9898-82

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15391080

  • £174.38 / 100µg


Estimated Shipment
01-03-2018
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

Description: This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44-kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. Cytokeratin 19 is expressed in a wide variety of simple and stratified epithelial tissue. Moreover, cytokeratin 19 expression can be induced by vitamin A, SV40 transformation, and cancer. A soluble form of cytokeratin 19 generated by caspase 3 cleavage has also been found to be secreted by cancer cells, thus possibly indicating tumor metastasis. Cytokeratin 19 often exists as a heterodimer with cytokeratin 7, a type II keratin.Applications Reported: This BA17 antibody has been reported for use in immunohistochemical staining and immunocytochemistry.Applications Tested: This BA17 antibody has been tested by immunocytochemistry on fixed and permeabilized MCF7 cells and can be used at less than or equal to 20 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filter Recommendation: When using this eFluor® 570 antibody conjugate, we recommend a filter that will capture the 570 emission wavelength (for example, Excitation 545/25, 565LP, Emission 605/70). A standard Alexa Fluor® 555 or TRITC filter is acceptable.Excitation: 555 nm; Emission: 570 nm
Specifications

Specifications

Cytokeratin 19
BA17
eFluor 570
Conjugated
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CK19, Keratin 19
IgG1
RUO
Primary
Human
Videos