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Cytokeratin 19 Mouse anti-Human, Alexa Fluor 488, Clone: BA17, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9898-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15540317

  • £161.27 / 100µg


Estimated Shipment date
from Supplier 03-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. Cytokeratin 19 is expressed in a wide variety of simple and stratified epithelial tissue. Moreover, cytokeratin 19 expression can be induced by vitamin A, SV40 transformation, and cancer. A soluble form of cytokeratin 19 generated by caspase 3 cleavage has also been found to be secreted by cancer cells, thus possibly indicating tumor metastasis. Cytokeratin 19 often exists as a heterodimer with cytokeratin 7, a type II keratin.
Description & Specifications

Specifications

Cytokeratin 19
BA17
Alexa Fluor 488
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry
0.5mg/mL
Conjugated
CK19, Keratin 19
IgG1
RUO
Primary
Human