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Cytokeratin 19, Alexa Fluor 488, clone: BA17, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9898-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15540317

  • £163.94 / 100µg


Estimated Shipment date
from Supplier 20-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44-kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. Cytokeratin 19 is expressed in a wide variety of simple and stratified epithelial tissue. Moreover, cytokeratin 19 expression can be induced by vitamin A, SV40 transformation, and cancer. A soluble form of cytokeratin 19 generated by caspase 3 cleavage has also been found to be secreted by cancer cells, thus possibly indicating tumor metastasis. Cytokeratin 19 often exists as a heterodimer with cytokeratin 7, a type II keratin.Applications Reported: This BA17 antibody has been reported for use in immunohistochemical staining and immunocytochemistry.Applications Tested: This BA17 antibody has been tested by immunocytochemistry on fixed and permeabilized cells and can be used at less than or equal to 10 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Cytokeratin 19
BA17
Alexa Fluor 488
Conjugated
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CK19, Keratin 19
IgG1
RUO
Primary
Human
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