Cytokeratin 18 Mouse anti-Human, Alexa Fluor 488, Clone: LDK18, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9815-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15530307

Quantity Price
1 £ 73.93 / 25µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Species Reactivity Human
Isotype IgG1
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Microscopy
Concentration 0.5mg/mL
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone LDK18
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Host Species Mouse
Conjugate Alexa Fluor 488
Antigen Cytokeratin 18

The monoclonal antibody LDK18 recognizes human Cytokeratin 18. Cytokeratin 18 is member of the large family of intermediate filaments found within epithelial cells. The family of cytokeratins is made up of type I (acidic) and type II (basic) members which form heterodimers by pairing an acidic with a basic member to compose the keratin filament. Cytokeratin 18 (type I) is most commonly found associated with cytokeratin 8 (type II). Because many tumors of epithelial origin retain expression of keratin proteins, cytokeratin 18 has been used as a tumor marker to identify both tumors and metastases. In addition, cytokeratin 18 has been shown to be expressed in highly proliferative retinal pigment epithelium cells.