Cytokeratin 18 Antibody (KRT18/836) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-48066

Product Code. 18153289

Description

Cytokeratin 18 Monoclonal specifically detects Cytokeratin 18 in Human, Canine, Feline, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin 18
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: KRT18
• Immunogen: Recombinant full-length human Cytokeratin 18 protein (Uniprot: P05783)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
• Clone: KRT18/836
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array
• Gene Alias: Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
• Host Species: Mouse
• Molecular Weight of Antigen: 45 kDa
• Quantity: 7 mL
• Research Discipline: Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers
• Gene ID (Entrez): 3875
• Target Species: Human, Canine, Feline, Rat (Negative)
• Form: Purified