CXCL12 alpha (SDF-1 alpha), Polyclonal, eBioscience™
Rabbit Polyclonal Antibody
Brand: Affymetrix eBioscience 14-7992-83
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: The polyclonal antibody reacts with both mouse and rat SDF-1 alpha. It was was generated using E. coli-expressed N terminal amio acids 20-89 of mouse SDF-1 alpha as an immunogen. SDF-1 alpha (stromal cell-derived factor-1 alpha), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of the SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.Applications Reported: This polyclonal has been reported for use in immunoblotting (WB), immunoprecipitation, and immunohistochemistry. Cross-reactivity to SDF-1 alpha of other species has not been determined.Applications Tested: To achieve best results, titrate antibody by dilution for each application as follows:Western Blot 1:1000Immunoprecipitation 1:300-500Immunohistochemistry 1:100-500.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|CXCL12 alpha (SDF-1 alpha)|
|Store at 2-8°C.|
|ImmunohistochemistryþImmunohistochemistry (Frozen)þImmunoprecipitationþWestern Blot|
|PBS with 0.09% sodium azide; pH 7.2|
|SDF-1 alpha, SDF-1a, SDF1a|
For Research Use Only.