CXCL12 alpha (SDF-1 alpha) Rabbit anti-Mouse, Rat, Polyclonal, eBioscience™

Rabbit Polyclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-7992-83

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15218097

Quantity Price
1 £ 121.67 / 200µg
EU Stock 2
Add to basket


Description and Specification

Specification

Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blot
Formulation aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary. The 50μg size of this antibody is supplied in liquid form. The 200μg size of this antibody may be supplied in liquid or lyophilized powder forms.
Gene Alias SDF-1 alpha, SDF-1a, SDF1a
Isotype IgG
Storage Requirements Store at 2-8°C.
Host Species Rabbit
Antigen CXCL12 alpha (SDF-1 alpha)
Species Reactivity Mouse, Rat
Conjugate Unlabeled
Format Purified
Primary or Secondary Primary
Regulatory Status RUO
Monoclonal or Polyclonal Polyclonal
Quantity 200μg

The polyclonal antibody reacts with both mouse and rat SDF-1 alpha. It was was generated using E. coli-expressed N terminal amio acids 20-89 of mouse SDF-1 alpha as an immunogen. SDF-1 alpha (stromal cell-derived factor-1 alpha), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of the SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.