CXCL12 alpha (SDF-1 alpha), Polyclonal, eBioscience™
Rabbit Polyclonal Antibody
Brand: Affymetrix eBioscience 14-7992-81
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: The polyclonal antibody reacts with both mouse and rat SDF-1 alpha. It was was generated using E. coli-expressed N terminal amio acids 20-89 of mouse SDF-1 alpha as an immunogen. SDF-1 alpha (stromal cell-derived factor-1 alpha), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of the SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.Applications Reported: This polyclonal has been reported for use in immunoblotting (WB), immunoprecipitation, and immunohistochemistry. Cross-reactivity to SDF-1 alpha of other species has not been determined.Applications Tested: To achieve best results, titrate antibody by dilution for each application as follows:Western Blot 1:1000Immunoprecipitation 1:300-500Immunohistochemistry 1:100-500.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|CXCL12 alpha (SDF-1 alpha)|
|Store at 2-8°C.|
|aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary. The 50μg size of this antibody is supplied in liquid form. The 200μg size of this antibody may be supplied in liquid or lyophilized powder forms.|
|SDF-1 alpha, SDF-1a, SDF1a|
For Research Use Only.