CXCL10 (IP-10) Mouse anti-Human, PE, Clone: 4NY8UN, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9744-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15547226

Quantity Price
1 £ 78.88 / 25 tests
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Gene Alias Interferon Inducible Protein-10, CXC Motif Chemokine 10
Isotype IgG2b
Primary or Secondary Primary
Antigen CXCL10 (IP-10)
Applications Flow Cytometry (Intracellular Staining)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone 4NY8UN
Quantity 25 tests
Species Reactivity Human
Host Species Mouse
Concentration 5μL (0.125μg)/test
Format Conjugated
Conjugate PE

This 4NY8UN monoclonal antibody reacts with human CXCL10. CXCL10, also known as Interferon Inducible Protein-10 (IP-10), is a member of the CXC family of chemokines. It is secreted by monocytes, epithelial cells, and endothelial cells in response to IFN gamma or other pro-inflammatory cytokines and stimuli. CXCL10 signaling is mediated by the G protein-coupled receptor CXCR3, which is expressed on activated T cells and plays an important role in directing the migration of T cells, especially during Th1 responses. In addition to its chemotactic functions, CXCL10 is a potent inhibitor of angiogenesis and tumor growth and modulates expression of adhesion molecules. Elevated levels of CXCL10 are observed in response to allergic inflammation, various infections, and Alzheimer’s disease.