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CX3CR1 Rat anti-Human, PE, Clone: 2A9-1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-6099-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15547066

  • £72.77 / 25 tests


Estimated Shipment date
from Supplier 29-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.
Description & Specifications

Specifications

CX3CR1
2A9-1
PE
Conjugated
Rat
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Chemokine C-X3-C receptor 1, V28
IgG2b
RUO
Primary
Human