CX3CR1 Rat anti-Human, PE, Clone: 2A9-1, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-6099-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15557066

Quantity Price
1 £ 188.93 / 100 tests
Estimated Shipment date
from Supplier 05-05-2017
Add to basket


Description and Specification

Specification

Quantity 100 Tests
Applications Flow Cytometry
Conjugate PE
Species Reactivity Human
Primary or Secondary Primary
Clone 2A9-1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Gene Alias Chemokine C-X3-C receptor 1, V28
Host Species Rat
Regulatory Status RUO
Antigen CX3CR1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Isotype IgG2b
Concentration 5μL (0.125μg)/test

This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.