CX3CR1 Rat anti-Human, Biotin, Clone: 2A9-1, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-6099-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15320000

Quantity Price
1 £ 170.59 / 100µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Antigen CX3CR1
Quantity 100μg
Regulatory Status RUO
Clone 2A9-1
Applications Flow Cytometry
Conjugate Biotin
Monoclonal or Polyclonal Monoclonal
Gene Alias Chemokine C-X3-C receptor 1, V28
Species Reactivity Human
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2b
Concentration 0.5mg/mL
Host Species Rat
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze.

This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.